Atypical scleromyxedema presenting with cutaneous and cardiovascular manifestations

Abstract

Sue-Ann Teh,1 David A Kandiah2 1Department of Health Western Australia, Bunbury Hospital, Bunbury, 2School of Psychiatry and Clinical Neurosciences, Faculty of Medicine, Dentistry and Health Sciences, University of Western Australia, Crawley, WA, Australia Abstract: Scleromyxedema is part of a group of cutaneous mucinoses, characterized by a generalized papular eruption, dermal mucin deposition, and an increase in dermal collagen. This condition can be localized as discrete papular lichen myxedematous skin or as a systemic condition usually associated with paraproteinaemia. To date, there is no unifying treatment and is limited by rarity, small number of case reports, and the lack of randomized controlled trials. We describe the case of a 56-year-old gentleman with features of scleromyxedema who had cutaneous and cardiac involvement, and significant mediastinal lymphadenopathy without monoclonal gammopathy. Keywords: scleromyxedema, heart failure, dermal mucin

Keywords

• Scleromyxedema
• Heart failure
• Dermal mucin