Corrigendum to: External Validation of the eCura System for Undifferentiated-Type Early Gastric Cancer with Noncurative Endoscopic Resection
Hyo-Joon Yang,
Young-Il Kim,
Ji Yong Ahn,
Kee Don Choi,
Sang Gyun Kim,
Seong Woo Jeon,
Jie-Hyun Kim,
Sung Kwan Shin,
Hyuk Lee,
Wan Sik Lee,
Gwang Ha Kim,
Jae Myung Park,
Woon Geon Shin,
Il Ju Choi
Affiliations
Hyo-Joon Yang
Division of Gastroenterology, Department of Internal Medicine and Gastrointestinal Cancer Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
Young-Il Kim
Center for Gastric Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea
Ji Yong Ahn
Division of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Kee Don Choi
Division of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Sang Gyun Kim
Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea
Seong Woo Jeon
Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea
Jie-Hyun Kim
Department of Internal Medicine, Institute of Gastroenterology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
Sung Kwan Shin
Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea
Hyuk Lee
Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
Wan Sik Lee
Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea
Gwang Ha Kim
Department of Internal Medicine, Pusan National University College of Medicine, Busan, Korea
Jae Myung Park
Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
Woon Geon Shin
Department of Internal Medicine, Institute for Liver and Digestive Diseases, Hallym University College of Medicine, Chuncheon, Korea
Il Ju Choi
Center for Gastric Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea
Background/Aims: The combinatorial effects of prophylactic methods for postendoscopic retrograde cholangiopancreatography pancreatitis (PEP) in patients with risk factors remain unclear. In this network meta-analysis, we compared the efficacy of various prophylactic strategies to decrease the risk of PEP among patients with risk factors. Methods: A systematic review was performed to identify randomized controlled trials from PubMed, Embase, and the Cochrane Library through July 2021. We used frequentist network meta-analysis to compare the rates of PEP among patients who received prophylactic treatments as follows: class A, rectal nonsteroidal anti-inflammatory drugs; class B, prophylactic pancreatic stent; class C, aggressive hydration; or control, no prophylaxis or active control. We selected those studies that included patients with risk factors for PEP. Results: We identified 19 trials, comprising 4,328 participants. Class ABC (odds ratio [OR], 0.08; 95% confidence interval [CI], 0.03 to 0.24), class AC (OR, 0.10; 95% CI, 0.02 to 0.47), class AB (OR, 0.12; 95% CI, 0.05 to 0.26), class BC (OR, 0.13; 95% CI, 0.04 to 0.41), class A (OR, 0.16; 95% CI, 0.05 to 0.50), and class B (OR, 0.26; 95% CI, 0.14 to 0.46), were associated with a reduced risk of PEP as compared to that of the control. The most effective prophylaxis was ABC (0.87), followed by AC (0.68), AB (0.65), BC (0.56), A (0.49), and B (0.24) according to P-score. Conclusions: The results of this network meta-analysis suggest that the more prophylactic methods are employed, the better the outcomes. It appears that for patients with risk factors, we need to prevent PEP through the use of these well proven combination strategies.
