Revista Brasileira de Hematologia e Hemoterapia (Jan 2011)
Disease progression after R-CHOP treatment associated with the loss of CD20 antigen expression
Abstract
A case of a follicular lymphoma transformed into a CD20+ is described which progressed with the loss of CD20 expression after 8 cycles of R-CHOP. This phenomenon is not a rare event and has shown poor prognosis. Our purposes are to describe this event and suggest biopsy in relapsed or progressive disease.
Keywords