Reliability of dynamic susceptibility contrast perfusion metrics in pre- and post-treatment glioma

Abstract

Highlights • DSC-MR perfusion imaging measurements in non-treated glioma is highly reliable between readers, even readers with little experience. • DSC-MR perfusion imaging measurements in treated glioma is show to be inconsistent between readers. • When using DSC-MR perfusion imaging as a quantitative surveillance tool for the recurrence of glioma after treatment, double-reading should be preferred.

Keywords

• Dynamic susceptibility contrast magnetic resonance (DSC-MR) perfusion imaging
• Glioma
• Interobserver variability
• Region of interest