mSystems (Jun 2021)
Component Parts of Bacteriophage Virions Accurately Defined by a Machine-Learning Approach Built on Evolutionary Features
- Tze Y. Thung,
- Murray E. White,
- Wei Dai,
- Jonathan J. Wilksch,
- Rebecca S. Bamert,
- Andrea Rocker,
- Christopher J. Stubenrauch,
- Daniel Williams,
- Cheng Huang,
- Ralf Schittelhelm,
- Jeremy J. Barr,
- Eleanor Jameson,
- Sheena McGowan,
- Yanju Zhang,
- Jiawei Wang,
- Rhys A. Dunstan,
- Trevor Lithgow
Affiliations
- Tze Y. Thung
- Infection & Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia
- Murray E. White
- Infection & Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia
- Wei Dai
- Infection & Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia
- Jonathan J. Wilksch
- Infection & Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia
- Rebecca S. Bamert
- Infection & Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia
- Andrea Rocker
- Infection & Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia
- Christopher J. Stubenrauch
- ORCiD
- Infection & Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia
- Daniel Williams
- Infection & Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia
- Cheng Huang
- Monash Proteomics & Metabolomics Facility, Monash University, Clayton, Australia
- Ralf Schittelhelm
- Monash Proteomics & Metabolomics Facility, Monash University, Clayton, Australia
- Jeremy J. Barr
- ORCiD
- Centre to Impact AMR, Monash University, Clayton, Australia
- Eleanor Jameson
- School of Life Sciences, University of Warwick, Coventry, United Kingdom
- Sheena McGowan
- Infection & Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia
- Yanju Zhang
- School of Computer Science and Information Security, Guilin University of Electronic Technology, Guilin, China
- Jiawei Wang
- ORCiD
- Infection & Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia
- Rhys A. Dunstan
- Infection & Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia
- Trevor Lithgow
- ORCiD
- Infection & Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia
- DOI
- https://doi.org/10.1128/mSystems.00242-21
- Journal volume & issue
-
Vol. 6,
no. 3
Abstract
In response to the global problem of antimicrobial resistance, there are moves to use bacteriophages (phages) as therapeutic agents. Selecting which phages will be effective therapeutics relies on interpreting features contributing to shelf-life and applicability to diagnosed infections.
