(<i>E</i>)-1-(5-Methyl-1-(4-nitrophenyl)-1<i>H</i>-1,2,3-triazol-4-yl)ethan-1-one Oxime

Abstract

The reaction of 1-(5-methyl-1-(4-nitrophenyl)-1H-1,2,3-triazol-4-yl)ethan-1-one (1) with excess hydroxylamine hydrochloride (2 mole equivalents) in dry ethanol afforded (E)-1-(5-methyl-1-(4-nitrophenyl)-1H-1,2,3-triazol-4-yl)ethan-1-one oxime (2) in 86% yield. The structure of the new heterocycle 2 was confirmed using nuclear magnetic resonance spectroscopy, single crystal X-ray and elemental analysis.

Keywords

• triazoles
• oximes
• hydroxylamine hydrochloride
• X-ray diffraction
• heterocycles
• synthesis