Case Reports in Oncology (Oct 2023)

Giant Mature Ovarian Cystic Teratoma in a Pediatric Patient: Case Report and Literature Review

  • Adolfo Eduard Barragán-Curiel,
  • Carlos Murillo-Zepeda,
  • Karla Fernanda Castro-Perez,
  • Francisco Omar Alcalá-Aguirre,
  • Lilian Sabinne Díaz-Montoya,
  • Omar Alfonso Ruiz-Félix,
  • José Antonio Acevedo-Delgado,
  • Moyra Velasco-Preciado

DOI
https://doi.org/10.1159/000534141
Journal volume & issue
Vol. 16, no. 1
pp. 1066 – 1072

Abstract

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Mature cystic teratomas, also called dermoid cysts, are the most common germ-cell ovarian neoplasms in children. On average, ovarian dermoid cysts are slow-growing neoplasms with a mean size between 6.4 and 7.0 cm that enlarge at a rate of 1.8 mm/year; however, these can reach large dimensions. Giant ovarian tumors are defined as those having a maximum diameter equal to or more than 15 cm; these represent a therapeutic challenge as they increase the risk of wide wound size and surgical invasiveness. In this paper, we present a case of a 10-year-old Hispanic female that complained of abdominal pain, distension, and nausea. Physical examination revealed a mass on the left side of the abdomen and an axial computed tomography found a large pelvic tumor extending to the abdominal region. After a laparotomy approach, pathology evaluation confirmed the diagnosis of mature cystic teratoma. The patient recovered thoroughly and had no complications at a 6-month follow-up. We conducted a literature review including English and Spanish reports about giant ovarian teratomas; we retrieved 16 cases from 2003 to 2023. We concluded that giant ovarian tumors may be underreported, particularly in resource-limited areas where tumors might grow unrecognized, and that English-language bias might play a substantial role in literature reviews involving case reports and case series.