BMC Medical Genomics (Jan 2024)

A brief comparison of polygenic risk scores and Mendelian randomisation

  • Victoria Garfield,
  • Emma L. Anderson

DOI
https://doi.org/10.1186/s12920-023-01769-4
Journal volume & issue
Vol. 17, no. 1
pp. 1 – 4

Abstract

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Abstract Mendelian randomisation and polygenic risk score analysis have become increasingly popular in the last decade due to the advent of large-scale genome-wide association studies. Each approach has valuable applications, some of which are overlapping, yet there are important differences which we describe here.

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