Dynamics of main epidemiological characteristics of type 1 diabetes mellitus in children of the Russian Federation

Abstract

Aim. To assess main epidemiological characteristics (prevalence, morbidity, mortality) of type 1 diabetes mellitus (DM1) in children of the RussianFederation and its federal okrugs (districts) in 2001-2008. Materials and methods. The research was based on questionnaries designed in the Pediatric Endocrinology Institute of Endocrinology Research Center. Results. There were18,028 children aged 0-14 years with DM1 as per 01.01.2009. As many as 2,789 new caseswere diagnosed in 2008. The meanprevalence as per 01.01.2009 was estimated at 72.28 (24.88-90.63), morbidity 11.25 (3.39-14.06), mortality 0.07 (0-0.26) per 100,000 childrenspopulation.The absolute increment in morbidity from 2001 to 2008 was 1.69, growth rate 117.7%, accession rate 17.7%, mean annual rate for the8-year study period 2.2%. Morbidity is predicted to reach 13.2 per 100,000 in the next 5 years (2013). The highest morbidity recorded in the Uralokrug (14.73/100,000) exceeded that in the North-West okrug (13.63/100,000 as per 01.01.2009) where it was maximum in the preceding years.Morbidity in the Privollzhsky, Far East and Siberian okrugs remained unaltered (11.06, 7.3, 10.6 respectively), decreased in the Southern okrug(8.0) and increased in the Central okrug from 13.3 in 2007 to 14.3/100,000 in 2008. The overall prevalence of DM1 among children in Russia increasedfrom 54.6 to 72.28 per 100,000. Conclusion. The main tendentious in DM1 epidemiology in children in RF are comparable with those worldwide.

Keywords

• epidemiology
• type 1 diabetes mellitus
• children
• morbidity
• prevalence
• mortality