Evidence for a contribution by the intestinal wall to the serum cholesterol of the rat

Abstract

Rats were fed cholesterol in order to block hepatic cholesterol synthesis, and their intestinal lymph ducts were cannulated. Experiments with these rats showed that cholesterol synthesized in the intestinal wall enters into the circulating cholesterol pool. The quantitative significance of this source of serum cholesterol has not been established.

Keywords

• cholesterol
• serum
• lymph
• biosynthesis
• intestinal wall
• lymph duct cannulation