Indian Journal of Medical and Paediatric Oncology (Apr 2025)

Spectrum of Somatic Malignancy in Testicular Germ Cell Tumors—A Histopathological Review of 25 Cases with Clinical Outcome

  • Priyadarsani Subramanian,
  • Amandeep Arora,
  • Mahendra Pal,
  • Gagan Prakash,
  • Priyamvada Maitre,
  • Vedang Murthy,
  • Amit Joshi,
  • Swapnil Rane,
  • Sangeeta Desai,
  • Santosh Menon

DOI
https://doi.org/10.1055/s-0044-1788307
Journal volume & issue
Vol. 46, no. 02
pp. 174 – 182

Abstract

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Introduction Germ cell tumors (GCTs) are the commonest testicular malignancy in young males. These tumors are highly chemoresponsive, however become resistant to conventional therapy when a somatic-type malignancy (SM) develops, which happens in ∼3 to 6% of the cases.

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