A CRISPR Interference Screen of Essential Genes Reveals that Proteasome Regulation Dictates Acetic Acid Tolerance in Saccharomyces cerevisiae

mSystems (Aug 2021)

Affiliations

Vaskar Mukherjee: ORCiD; Department of Biology and Biological Engineering, Division of Industrial Biotechnology, Chalmers University of Technology, Gothenburg, Sweden
Ulrika Lind: ORCiD; Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden
Robert P. St. Onge: ORCiD; Stanford Genome Technology Center, Stanford University, Palo Alto, California, USA
Anders Blomberg: ORCiD; Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden
Yvonne Nygård: ORCiD; Department of Biology and Biological Engineering, Division of Industrial Biotechnology, Chalmers University of Technology, Gothenburg, Sweden

Abstract

Acetic acid is inhibitory to the growth of the yeast Saccharomyces cerevisiae