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An Ultrastructural Study of Langerhans Cells in the Depigmentation Skin in Vitiligo

Indian Journal of Dermatology, Venereology and Leprology. 1987;53(2):98-101


Journal Homepage

Journal Title: Indian Journal of Dermatology, Venereology and Leprology

ISSN: 0378-6323 (Print); 0973-3922 (Online)

Publisher: Wolters Kluwer Medknow Publications

Society/Institution: Indian Association of Dermatologists, Venereologists and Leprologists

LCC Subject Category: Medicine: Dermatology

Country of publisher: India

Language of fulltext: English

Full-text formats available: PDF, HTML, ePUB



Haii Shamim Osman

N Lata Mehta


Blind peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 44 weeks


Abstract | Full Text

The role of Langerhans cells in the pathogenesis of vitiligo is as yet unresolved. Ultrastructurally, these cells are identified by the presence of Birpeck granules, but at times this morphological marker is missed during′ sectioning. Identification of Langerhans cells was done by monoclonal antibodies and these were quantitated in the depigmented and the pigmented skin of seven vitiligo patients. Observations are in favour of autoimmunity being an aetiological factor for vitiligo.