CyTOF Profiling of Zika and Dengue Virus-Infected Human Peripheral Blood Mononuclear Cells Identifies Phenotypic Signatures of Monotype Subsets and Upregulation of the Interferon-Inducible Protein CD169
Rafael Fenutria,
Kevin Maringer,
Uma Potla,
Dabeiba Bernal-Rubio,
Matthew J. Evans,
Eva Harris,
Adeeb H. Rahman,
Ana Fernandez-Sesma,
Irene Ramos
Affiliations
Rafael Fenutria
Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Kevin Maringer
Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Uma Potla
Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Dabeiba Bernal-Rubio
Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Matthew J. Evans
Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Eva Harris
Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, California, USA
Adeeb H. Rahman
Human Immune Monitoring Center, Icahn School of Medicine at Mt. Sinai, New York, New York, USA
Ana Fernandez-Sesma
Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Zika and dengue viruses are emergent arboviruses of great public health impact. Both viruses are responsible for important diseases, yet there is currently no vaccine or specific treatment available.
