Target Identification of a Class of Pyrazolone Protein Aggregation Inhibitor Therapeutics for Amyotrophic Lateral Sclerosis
Pathum M. Weerawarna,
Isaac T. Schiefer,
Pedro Soares,
Susan Fox,
Richard I. Morimoto,
Rafael D. Melani,
Neil L. Kelleher,
Chi-Hao Luan,
Richard B. Silverman
Affiliations
Pathum M. Weerawarna
Department of Chemistry, Chemistry of Life Processes Institute, Center for Developmental Therapeutics, Northwestern University, Evanston, Illinois, United States
Isaac T. Schiefer
Department of Chemistry, Chemistry of Life Processes Institute, Center for Developmental Therapeutics, Northwestern University, Evanston, Illinois, United States
Pedro Soares
Department of Chemistry, Chemistry of Life Processes Institute, Center for Developmental Therapeutics, Northwestern University, Evanston, Illinois, United States
Susan Fox
Department of Molecular Biosciences, Northwestern University, Evanston, Illinois, United States
Richard I. Morimoto
Department of Molecular Biosciences, Northwestern University, Evanston, Illinois, United States
Rafael D. Melani
Department of Chemistry and Proteomics Center of Excellence, Northwestern University, Evanston, Illinois, United States
Neil L. Kelleher
Department of Chemistry, Chemistry of Life Processes Institute, Center for Developmental Therapeutics, Northwestern University, Evanston, Illinois, United States
Chi-Hao Luan
High Throughput Analysis Laboratory, Chemistry of Life Processes Institute, and Department of Molecular Biosciences, Northwestern University, Evanston, Illinois, United States
Richard B. Silverman
Department of Chemistry, Chemistry of Life Processes Institute, Center for Developmental Therapeutics, Northwestern University, Evanston, Illinois, United States
