Rheumatology (Jun 2024)

An epidemiological study of multisystem inflammatory syndrome in children (MIS-C) and young adults among COVID-19-positive patients – data from National Inpatient Sample database

  • Shruti Aggarwal,
  • Jasninder Singh Dhaliwal,
  • Nomesh Kumar,
  • Hemamalini Sakthivel,
  • Raheel Ahmed,
  • Renuka Verma,
  • Kamleshun Ramphul

DOI
https://doi.org/10.5114/reum/189213
Journal volume & issue
Vol. 62, no. 3
pp. 214 – 216

Abstract

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During the pandemic of COVID-19, a novel atypical set of clinical findings was seen among several children with recent or current exposure to the virus. It was termed the “multisystem inflammatory syndrome in children” (MIS-C). Our study used the 2021 National Inpatient Sample to study the associations of sex, race, and age with the incidence of MIS-C among COVID-19-positive children. Out of 69,440 COVID-19-positive children, 2,790 (4.0%) reported MIS-C. The incidence of MIS-C was highest among those aged 8 years old (17,130 MIS-C cases per 100,000 COVID-19 patients), Asian or Pacific Islanders (API) (5,346 MIS-C per 100,000 COVID-19 cases), and males (4,734 cases per 100,000 COVID-19 cases). Furthermore, 7.9% of MIS-C cases met the classification of Kawasaki disease.

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