Thymic hyperplasia after mRNA based Covid-19 vaccination

Julia von Tresckow, Dr.; Bastian von Tresckow, PD Dr.; H. Christian Reinhardt, Professor; Ken Herrmann, Professor; Christoph Berliner, Dr.

Radiology Case Reports (Dec 2021)

Thymic hyperplasia after mRNA based Covid-19 vaccination

Julia von Tresckow, Dr.,
Bastian von Tresckow, PD Dr.,
H. Christian Reinhardt, Professor,
Ken Herrmann, Professor,
Christoph Berliner, Dr.

Affiliations

Julia von Tresckow, Dr.: Department of Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; Corresponding author.
Bastian von Tresckow, PD Dr.: Department of Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
H. Christian Reinhardt, Professor: Department of Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
Ken Herrmann, Professor: Department of nuclear medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
Christoph Berliner, Dr.: Department of nuclear medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

Journal volume & issue: Vol. 16, no. 12
pp. 3744 – 3745

Abstract

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Reactive lymphadenopathy with increased 18F-Fluordeoxyglucose uptake in positron emission tomography/computed tomography scans is known after mRNA vaccination (BNT162B2, mRNA-1273) against severe acute respiratory syndrome coronavirus type 2. Besides this, increased 18F-Fluordeoxyglucose uptake in the thymus might occur after mRNA vaccination as shown in our case of a young patient with mantle cell lymphoma.Especially in patients with lymphoma but also in other patients with cancer it is critical to distinguish between immune responses and involvement of the disease to avoid inadequate treatment decisions.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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