Interdisciplinary Neurosurgery (Dec 2020)
De novo appearance of intracranial Rosai-Dorfman disease during long-term follow-up: A case report
Abstract
Surgical resection is the optimal treatment of intracranial Rosai-Dorfman disease (RDD). However, data on the long-term outcomes after total resection are extremely rare. We herein describe a 39-year-old man in whom de novo RDD appeared twice during the long-term follow-up after total resection in the lateral ventricle region. The first de novo lesion developed in the left sphenoid ridge 3 years after surgical resection. The sphenoid ridge lesion was completely resected. The second de novo lesion developed in the bilateral anterior clinoid processes 12 years after initial treatment. The patient underwent intensity-modulated radiotherapy and continued corticosteroid therapy. Long-term follow-up should be performed for intracranial RDD because repeated remission and recurrence are possible.
