Inherited missense variants that affect GFI1B function do not necessarily cause bleeding diatheses

• Rinske van Oorschot,
• Anna E. Marneth,
• Saskia M. Bergevoet,
• Maaike G.J.M. van Bergen,
• Kathelijne Peerlinck,
• Claire E. Lentaigne,
• Carolyn M. Millar,
• Sarah K. Westbury,
• Remi Favier,
• Wendy N. Erber,
• Ernest Turro,
• Joop H. Jansen,
• Willem H. Ouwehand,
• Harriet L. McKinney,
• NIHR BioResource Collaborative Group,
• Kate Downes,
• Kathleen Freson,
• Bert A. van der Reijden

Affiliations

Rinske van Oorschot

Department of Laboratory Medicine, Laboratory of Hematology, Radboudumc, Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands

Anna E. Marneth

Department of Laboratory Medicine, Laboratory of Hematology, Radboudumc, Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands

Saskia M. Bergevoet

Department of Laboratory Medicine, Laboratory of Hematology, Radboudumc, Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands

Maaike G.J.M. van Bergen

Department of Laboratory Medicine, Laboratory of Hematology, Radboudumc, Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands

Kathelijne Peerlinck

Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, University of Leuven, Belgium

Claire E. Lentaigne

Centre for Haematology, Hammersmith Campus, Imperial College Academic Health Sciences Centre, Imperial College London, UK

Carolyn M. Millar

Centre for Haematology, Hammersmith Campus, Imperial College Academic Health Sciences Centre, Imperial College London, UK;Imperial College Healthcare NHS Trust, London, UK

Sarah K. Westbury

School of Cellular and Molecular Medicine, University of Bristol, UK

Remi Favier

Service d’Hematologie Biologique, Assistance-Publique Hôpitaux de Paris, Centre de Référence des Pathologies Plaquettaires, Hôpital Armand Trousseau, Paris, France

Wendy N. Erber

School of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia;PathWest Laboratory Medicine, Nedlands, Western Australia, Australia

Ernest Turro

Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, UK;National Health Service Blood and Transplant (NHSBT), Cambridge Biomedical Campus, UK;NIHR BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, UK;Medical Research Council Biostatistics Unit, University of Cambridge, Forvie Site, Cambridge Biomedical Campus, UK

Joop H. Jansen

Department of Laboratory Medicine, Laboratory of Hematology, Radboudumc, Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands

Willem H. Ouwehand

Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, UK;National Health Service Blood and Transplant (NHSBT), Cambridge Biomedical Campus, UK;NIHR BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, UK;Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK;Strangeways Research Laboratory, The National Institute for Health Research (NIHR) Blood and Transplant Unit in Donor Health and Genomics at the University of Cambridge, UK;BHF Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke’s Hospital, Cambridge Biomedical Campus, UK

Harriet L. McKinney

Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, UK;National Health Service Blood and Transplant (NHSBT), Cambridge Biomedical Campus, UK;NIHR BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, UK

NIHR BioResource Collaborative Group

NIHR BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, UK

Kate Downes

Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, UK;National Health Service Blood and Transplant (NHSBT), Cambridge Biomedical Campus, UK;NIHR BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, UK

Kathleen Freson

Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, University of Leuven, Belgium;NIHR BioResource, Cambridge University Hospitals, Cambridge Biomedical Campus, UK

Bert A. van der Reijden

Department of Laboratory Medicine, Laboratory of Hematology, Radboudumc, Radboud Institute for Molecular Life Sciences (RIMLS), Nijmegen, the Netherlands