Demographic, clinical and diagnostic correlation of almond allergy in a cohort of nut allergy patients

Abstract

Tree nut anaphylaxis commonly categorizes almond as a potential allergen. However, large studies on allergic cohorts focused on almond allergy are rare. Food allergy is increasing globally. In parallel, almond consumption is increasing in developed nations. This study presents serological data in a large paediatric cohort of food anaphylaxis patients specifically assessing almond allergy risk. The purpose of this study is to describe the correlation of almond allergy specific to demographic, clinical and diagnostic markers in a cohort of 411 nut-allergic children. In this cohort with a history of food allergy, the prevalence of almond allergy was 67.6%. Approximately 25% of patients demonstrated both almond sensitivity (sIgE > 0.35 kU/L) and clinical reactivity (wheal size > 3 mm). Interestingly, peanut allergy was listed in the top 3 allergens of 71.8% of patients with almond sensitivity and reactivity. A better understanding of these relationships is essential as more patients are receiving personalized care.

Keywords

• allergy
• anaphylaxis
• immunotherapy
• almond
• ige
• peanut