Journal of Feline Medicine and Surgery Open Reports (Apr 2015)

Use of sildenafil citrate in a cat with Eisenmenger’s syndrome and an atrial septal defect

  • Ke Shuan Chow,
  • Niek J Beijerink,
  • Stephen Ettinger,
  • Reuben Fliegner,
  • Julia A Beatty,
  • Vanessa R Barrs

DOI
https://doi.org/10.1177/2055116915579680
Journal volume & issue
Vol. 1

Abstract

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A 2-year-old male neutered Siamese cat presenting with weakness and dyspnoea was diagnosed with an atrial septal defect and pulmonary hypertension, which resulted in right-to-left shunting (Eisenmenger’s syndrome). The cat was treated with sildenafil (0.25–0.6 mg/kg) for 10 months. There were no apparent treatment-related adverse effects. Improvement in clinical signs was noted, although increasing doses of sildenafil were required. After 10 months the cat significantly deteriorated and was euthanased.