Nature Communications (Sep 2021)

A longitudinal sampling study of transcriptomic and epigenetic profiles in patients with thrombocytopenia syndrome

  • Yafen Wang,
  • Shaoqing Han,
  • Ruoxi Ran,
  • Anling Li,
  • Huanyu Liu,
  • Mingjun Liu,
  • Yongwei Duan,
  • Xiong Zhang,
  • Zhigang Zhao,
  • Shihui Song,
  • Xiaocheng Weng,
  • Song-Mei Liu,
  • Xiang Zhou

DOI
https://doi.org/10.1038/s41467-021-25804-z
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 11

Abstract

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Severe fever with thrombocytopenia syndrome (SFTS) is an emerging hemorrhagic fever caused by tick-borne SFTS virus. Here, Wang et al. characterize transcriptomic and epigenetic changes in infected patients and correlate them with clinical parameters to improve the understanding of disease progression.