Spontaneous regression of lung metastases after transarterial chemoembolization for hepatocellular carcinoma

Naoko Kakuta, MD; Taku Yasumoto, MD, PhD; Yuichi Yoshida, MD, PhD; Manabu Tsuda, MD; Akito Miyazaki, MD; Satoshi Miyamoto, MD; Reiko Inada, MD; Hideki Yorifuji, MD, PhD; Yuichi Higami, MD, PhD; Satoshi Tetsumoto, MD, PhD; Masaki Miyazaki, MD, PhD; Yoshinori Katada, MD, PhD; Masafumi Naito, MD, PhD

Radiology Case Reports (Jun 2021)

Spontaneous regression of lung metastases after transarterial chemoembolization for hepatocellular carcinoma

Naoko Kakuta, MD,
Taku Yasumoto, MD, PhD,
Yuichi Yoshida, MD, PhD,
Manabu Tsuda, MD,
Akito Miyazaki, MD,
Satoshi Miyamoto, MD,
Reiko Inada, MD,
Hideki Yorifuji, MD, PhD,
Yuichi Higami, MD, PhD,
Satoshi Tetsumoto, MD, PhD,
Masaki Miyazaki, MD, PhD,
Yoshinori Katada, MD, PhD,
Masafumi Naito, MD, PhD

Affiliations

Naoko Kakuta, MD: Department of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Suita City, Osaka, Japan
Taku Yasumoto, MD, PhD: Department of Interventional Radiology, Miyakojima IGRT Clinic, 1-16-22, Miyakojima-hondori, Miyakojima-ku, Osaka City, Osaka, 534-0021, Japan; Corresponding author.
Yuichi Yoshida, MD, PhD: Department of Gastroenterology and Hepatology, Suita Municipal Hospital, Suita City, Osaka, Japan
Manabu Tsuda, MD: Department of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Suita City, Osaka, Japan
Akito Miyazaki, MD: Department of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Suita City, Osaka, Japan
Satoshi Miyamoto, MD: Department of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Suita City, Osaka, Japan
Reiko Inada, MD: Department of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Suita City, Osaka, Japan
Hideki Yorifuji, MD, PhD: Department of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Suita City, Osaka, Japan
Yuichi Higami, MD, PhD: Department of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Suita City, Osaka, Japan
Satoshi Tetsumoto, MD, PhD: Department of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Suita City, Osaka, Japan
Masaki Miyazaki, MD, PhD: Department of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Suita City, Osaka, Japan
Yoshinori Katada, MD, PhD: Department of Respiratory Medicine and Clinical Immunology, Suita Municipal Hospital, Suita City, Osaka, Japan
Masafumi Naito, MD, PhD: Department of Gastroenterology and Hepatology, Suita Municipal Hospital, Suita City, Osaka, Japan

Journal volume & issue: Vol. 16, no. 6
pp. 1530 – 1534

Abstract

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Spontaneous regressions of primary and/or metastatic lesions have been rarely reported in hepatocellular carcinoma (HCC). Herein, we report the case of a 71-year-old man with HCC, focusing on shape changes of lung metastases over time. Lung metastasis of HCC was histologically diagnosed by percutaneous computed tomography (CT)-guided needle biopsy after the treatment of primary HCC lesion. Lung lesions had been observed on enhanced contrast computed tomography for >3 years without any local or systemic treatment for them. During this period, treatments including surgical procedure for relapsed bladder cancer and transarterial chemoembolization for HCC were performed. Metastatic lung lesions immediately regressed after these treatments. Therefore, accumulation of such cases may help elucidate spontaneous regression mechanisms in primary HCC or its lung metastases.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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