Case Reports in Neurology (Nov 2022)

Multiple Endovascular Treatments for Hemorrhagic Cerebral Proliferative Angiopathy: A Case Report

  • Keijiro Shomura,
  • Tomoya Kamide,
  • Kouichi Misaki,
  • Taishi Tsutsui,
  • Iku Nambu,
  • Naoyuki Uchiyama,
  • Mitsutoshi Nakada

DOI
https://doi.org/10.1159/000527559
Journal volume & issue
Vol. 14, no. 3
pp. 433 – 440

Abstract

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Cerebral proliferative angiopathy (CPA) is a rare vascular abnormality characterized by transdural supply, stenoses of feeding arteries, and intermingled normal brain parenchyma in abnormal vessels. CPA is often regarded as a separate entity from “classical” brain arteriovenous malformations in angioarchitecture, natural history, clinical presentation, and treatment. Bleeding from CPA is uncommon, but once bleeding occurs, the risk of rebleeding is high. Herein, we describe a case of cerebral hemorrhage caused by CPA. We performed two different endovascular treatments: partial embolization with glue for a ruptured aneurysm and coil embolization for an unruptured growing aneurysm. To our knowledge, this is the first report of serial endovascular treatments for hemorrhagic CPA that included a ruptured aneurysm and a growing unruptured aneurysm.

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