Proceedings (Aug 2019)
Small Molecules as Potential Inhibitors of the 14-3-3/c-Abl Interaction for the Treatment of CML
- Leire Iralde-Lorente,
- Giusy Tassone,
- Ylenia Cau,
- Claire Munier,
- Lorenzo Franci,
- Cecilia Pozzi,
- Adriano Angelucci,
- Mario Chiariello,
- Matthew Perry,
- Stefano Mangani,
- Maurizio Botta
Affiliations
- Leire Iralde-Lorente
- Department of Biotechnology, Chemistry and Farmacy- Department of Excellence 2018-2022, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy
- Giusy Tassone
- Department of Biotechnology, Chemistry and Farmacy- Department of Excellence 2018-2022, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy
- Ylenia Cau
- Department of Biotechnology, Chemistry and Farmacy- Department of Excellence 2018-2022, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy
- Claire Munier
- Medicinal Chemistry, Respiratory, Inflammation and Autoimmunity, IMED Biotech Unit, AstraZeneca, SE-43183 Gothenburg, Sweden
- Lorenzo Franci
- Consiglio Nazionale delle Ricerche, Istituto di Fisiologia Clinica and University of Siena, Via Fiorentina 1, 53100 Siena, Italy
- Cecilia Pozzi
- Department of Biotechnology, Chemistry and Farmacy- Department of Excellence 2018-2022, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy
- Adriano Angelucci
- Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy
- Mario Chiariello
- Consiglio Nazionale delle Ricerche, Istituto di Fisiologia Clinica and University of Siena, Via Fiorentina 1, 53100 Siena, Italy
- Matthew Perry
- Medicinal Chemistry, Respiratory, Inflammation and Autoimmunity, IMED Biotech Unit, AstraZeneca, SE-43183 Gothenburg, Sweden
- Stefano Mangani
- Department of Biotechnology, Chemistry and Farmacy- Department of Excellence 2018-2022, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy
- Maurizio Botta
- Department of Biotechnology, Chemistry and Farmacy- Department of Excellence 2018-2022, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy
- DOI
- https://doi.org/10.3390/proceedings2019022017
- Journal volume & issue
-
Vol. 22,
no. 1
p. 17
Abstract
c-Abl is a tyrosine kinase implicated in the regulation of proliferation, adhesion, motility, andcell survival [...]
Keywords
