Beilstein Journal of Organic Chemistry (Jun 2013)

Homolytic substitution at phosphorus for C–P bond formation in organic synthesis

  • Hideki Yorimitsu

DOI
https://doi.org/10.3762/bjoc.9.143
Journal volume & issue
Vol. 9, no. 1
pp. 1269 – 1277

Abstract

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Organophosphorus compounds are important in organic chemistry. This review article covers emerging, powerful synthetic approaches to organophosphorus compounds by homolytic substitution at phosphorus with a carbon-centered radical. Phosphination reagents include diphosphines, chalcogenophosphines and stannylphosphines, which bear a weak P–heteroatom bond for homolysis. This article deals with two transformations, radical phosphination by addition across unsaturated C–C bonds and substitution of organic halides.

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