Nature Communications (Mar 2021)

Adult-born neurons immature during learning are necessary for remote memory reconsolidation in rats

  • Marie Lods,
  • Emilie Pacary,
  • Wilfrid Mazier,
  • Fanny Farrugia,
  • Pierre Mortessagne,
  • Nuria Masachs,
  • Vanessa Charrier,
  • Federico Massa,
  • Daniela Cota,
  • Guillaume Ferreira,
  • Djoher Nora Abrous,
  • Sophie Tronel

DOI
https://doi.org/10.1038/s41467-021-22069-4
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 14

Abstract

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The role of adult hippocampal neurogenesis in memory reconsolidation is unclear. Here, the authors show that memory retrieval activates both immature and mature adult-born neurons. However, only adult-born neurons immature during learning are required for remote memory reconsolidation in rats.