Left ventricular remodeling and diastolic function in patients with arterial hypertension and rheumatoid arthritis

Abstract

Pathologic left ventricular (LV) remodeling was registered in 96. 4 % of patients with arterial hypertension (AH) and rheumatoid arthritis (RA). For AH patients, concentric LV hypertrophy (LVH) was quite typical (85 %); RA patients demonstrated similar prevalence of all LVH types: eccentric LVH (22.3 % > ), concentric LVH (27.2 % > ), concentric remodeling (36.9 %). Ln individuals with RA and AH, LV remodeling structure was similar to that in RA-free hypertensive patients. For early RA debut, eccentric LVH was more typical; development of concentric LVH depended mostly on AH characteristics. Ln combination ofRA and AH, LV systolic dysfunction was relatively rare; at the same time, silent diastolic dysfunction (DD) was registered in 70 % > of cases. Silent DD, detected during stress echocardiography, was observed in 24 % > of patients with AH and RA; Type 1 DD - in 46 % >.

Keywords

• arterial hypertension
• rheumatoid arthritis
• heart remodeling
• left ventricular diastolic dysfunction