بررسی اثر خمیردندان حاوی عصاره آبی کلاله زعفران بر روی شاخص‏های لثه‏ای بیماران مبتلا به ژنژیویت مارژینال ژنرالیزه وابسته به پلاک دندانی

Abstract

Introduction: Gingivitis is an inflammatory disease involving gums. Saffron contains various forms of flavonoids, glycosides and anthocyanin compounds that are proved to have anti-inflammatory and antioxidant effects. This study evaluates the anti-inflammatory effects of Saffron on gingival indices in patients with marginal generalized plaque induced gingivitis. Materials & Methods: For this study, we used toothpastes containing aqueous extract of Saffron flower. 22 patients with generalized marginal gingivitis were chosen. Patients were randomly divided into two equal groups of test and placebo each group, pocket depth index (PD), gingival index (GI), plaque index (PI) and bleeding of probing index (BOP) were measured before and one month after use. Independent t test, Mann–Whitney test and Wilcoxon test were used for statistical analysis (P

Keywords

• Gingivitis
• Saffron
• gingival indices