Study on Neutrophil Lymphocyte ratio and Platelet lymphocyte ratio in COVID-19 from our prospective. A cross sectional study

Abstract

Background : Novel corona Virus disease 2019 has been declared as pandemic by WHO.It started from Wuhan, China and within less times spread has occurred through out the world .The whole world is facing a huge challenge to prevent the spread of the disease.Though there was a strong response and preventive measures taken at the onset of the pandemic but still its one of the fastest growing pandemic in India at present. Only a clear knowledge regarding the risk and complication of covid19 to the population helps in fighting out this pandemics. Methods : A cross sectional study of 50 COVID 19 cases confirmed by Real Time Reverse Transcriptase Polymerase Chain Reaction. In the current study , prevalance and severity was assessed at 95% confidence interval. Independent statistical T test and chi- square were used to test significance( p<0.05). Result: Out of 50 cases 20 are severe and 30 are non severe.Lymphocytopenia is one of the most important cardinal hematological feature seen in 60% of patients. It was observed in the current study that NLR & PLR was increased in severe cases.The Neutrophil to Lymphocyte ratio (NLR). is higher in severe cases (5.87±1.92) when compared to non severe cases (2.86±1.20) was statistically significant (p = 0.043). Platelet to Lymphocyte ratio (PLR) was higher in severe cases (282.08±57.85) as compared to non severe cases(216.24±36.35) and is statistically significant (p value =0.007). Conclusion: Current study declares, Neutrophil to Lymphocyte ratio (NLR)and Platelet to Lymphocyte ratio (PLR) may be considered as good diagnostic and prognostic risk evaluators in assessing the severity and progression of the novel corona disease 2019

Keywords

• novel corona disease 2019 ( covid 19 ) . neutrophil to lymphocyte ratio (nlr). platelet to lymphocyte ratio (plr)
• real time polymerase chain reaction (rtpcr)