Arquivos de Neuro-Psiquiatria (Jul 2024)

Regional-based static and dynamic alterations in Alzheimer disease: a longitudinal study

  • Kuppe Channappa Usha,
  • Honnenahally Ningappa Suma,
  • Abhishek Appaji

DOI
https://doi.org/10.1055/s-0044-1787761
Journal volume & issue
Vol. 82, no. 07
pp. 1 – 11

Abstract

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Background Alzheimer disease (AD) leads to cognitive decline and alters functional connectivity (FC) in key brain regions. Resting-state functional magnetic resonance imaging (rs-fMRI) assesses these changes using static-FC for overall correlation and dynamic-FC for temporal variability.

Keywords