Indian Journal of Ophthalmology (Jan 2023)

Case series of central retinal artery occlusion in COVID-19-associated rhino-orbital-cerebral mucormycosis

  • Gurudutt M Kamath,
  • Sangeetha Jeganathan,
  • Sreelakshmi Salim,
  • Reeja Mariam Antony,
  • Ajay R Kamath,
  • Harshitha Hiran

DOI
https://doi.org/10.4103/IJO.IJO_3123_22
Journal volume & issue
Vol. 71, no. 7
pp. 2904 – 2906

Abstract

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Rhino orbital Mucormycosis caused by filamentous fungus of mucoraceae family was considered a rare disease affecting immunocompromised and diabetics with ketoacidosis until the recent COVID 19 pandemic. We are presenting a series of six cases of Rhino orbital cerebral Mucormycosis with central retinal artery occlusion. All six cases had common history of COVID 19 infection in recent past with sinusitis, proptosis and total ophthalmoplegia with central retinal artery occlusion on presentation. MR imaging showed invasive pan sinusitis with orbital and cerebral involvement. Urgent debridement was done and histopathological examination showed broad, filamentous aseptate fungi suggestive of Mucormycosis. All patients inspite of intravenous Amphotericin B with local debridement did not show any improvement and expired within a week of presentation. Hence our study shows poor prognosis of post covid 19 associated Mucormycosis with central retinal artery occlusion.

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