Anais Brasileiros de Dermatologia (Aug 2021)

Interstitial lung disease due to anti-TNF use in the treatment of psoriasis

  • Débora Dorneles Cunha de Queiroz Turíbio,
  • Francisco Clitson Sousa Oliveira,
  • Sandra Maria Fonseca Barreto,
  • Thaís Barros Felippe Jabour

DOI
https://doi.org/10.1016/j.abd.2020.08.016
Journal volume & issue
Vol. 96, no. 4
pp. 447 – 450

Abstract

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Abstract Psoriasis is a chronic inflammatory disease that affects the skin variably, according to genetic and environmental factors. Some patients may benefit from systemic treatment with immunobiological agents, drugs that can be accompanied by several adverse effects. A case of a 58-year-old patient undergoing treatment for psoriasis with adalimumab for five years is reported. Alterations compatible with interstitial pneumonia were detected with important regression after adalimumab discontinuation. This case is relevant due to the scarcity of reports on late pulmonary adverse effect of anti-TNF treatment of psoriasis.

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