Frigid Zone Medicine (Apr 2024)
Long non-coding RNA-AK138945 regulates myocardial ischemia-reperfusion injury via the miR-1-GRP94 signaling pathway
- Wang Yanying,
- Huang Jian,
- Sun Han,
- Liu Jie,
- Shao Yingchun,
- Gong Manyu,
- Yang Xuewen,
- Liu Dongping,
- Wang Zhuo,
- Li Haodong,
- Zhang Yanwei,
- Zhang Xiyang,
- Du Zhiyuan,
- Leng Xiaoping,
- Jiao Lei,
- Zhang Ying
Affiliations
- Wang Yanying
- State Key Laboratory of Frigid Zone Cardiovascular Diseases, and Pharmacology Department of Pharmacy college of Harbin Medical University, Harbin150081, China
- Huang Jian
- The Fourth Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin150040, China
- Sun Han
- State Key Laboratory of Frigid Zone Cardiovascular Diseases, and Pharmacology Department of Pharmacy college of Harbin Medical University, Harbin150081, China
- Liu Jie
- State Key Laboratory of Frigid Zone Cardiovascular Diseases, and Pharmacology Department of Pharmacy college of Harbin Medical University, Harbin150081, China
- Shao Yingchun
- State Key Laboratory of Frigid Zone Cardiovascular Diseases, and Pharmacology Department of Pharmacy college of Harbin Medical University, Harbin150081, China
- Gong Manyu
- State Key Laboratory of Frigid Zone Cardiovascular Diseases, and Pharmacology Department of Pharmacy college of Harbin Medical University, Harbin150081, China
- Yang Xuewen
- State Key Laboratory of Frigid Zone Cardiovascular Diseases, and Pharmacology Department of Pharmacy college of Harbin Medical University, Harbin150081, China
- Liu Dongping
- State Key Laboratory of Frigid Zone Cardiovascular Diseases, and Pharmacology Department of Pharmacy college of Harbin Medical University, Harbin150081, China
- Wang Zhuo
- Department of Ultrasound Imaging, the Second Affiliated Hospital of Harbin Medical University, Harbin150086, China
- Li Haodong
- State Key Laboratory of Frigid Zone Cardiovascular Diseases, and Pharmacology Department of Pharmacy college of Harbin Medical University, Harbin150081, China
- Zhang Yanwei
- State Key Laboratory of Frigid Zone Cardiovascular Diseases, and Pharmacology Department of Pharmacy college of Harbin Medical University, Harbin150081, China
- Zhang Xiyang
- State Key Laboratory of Frigid Zone Cardiovascular Diseases, and Pharmacology Department of Pharmacy college of Harbin Medical University, Harbin150081, China
- Du Zhiyuan
- State Key Laboratory of Frigid Zone Cardiovascular Diseases, and Pharmacology Department of Pharmacy college of Harbin Medical University, Harbin150081, China
- Leng Xiaoping
- Department of Ultrasound Imaging, the Second Affiliated Hospital of Harbin Medical University, Harbin150086, China
- Jiao Lei
- State Key Laboratory of Frigid Zone Cardiovascular Diseases, and Pharmacology Department of Pharmacy college of Harbin Medical University, Harbin150081, China
- Zhang Ying
- State Key Laboratory of Frigid Zone Cardiovascular Diseases, and Pharmacology Department of Pharmacy college of Harbin Medical University, Harbin150081, China
- DOI
- https://doi.org/10.2478/fzm-2024-0004
- Journal volume & issue
-
Vol. 4,
no. 1
pp. 31 – 40
Abstract
Myocardial ischemia-reperfusion injury (MIRI) is one of the leading causes of death from cardiovascular disease in humans, especially in individuals exposed to cold environments. Long non-coding RNAs (lncRNAs) regulate MIRI through multiple mechanisms.This study explored the regulatory effect of lncRNA-AK138945 on myocardial ischemia-reperfusion injury and its mechanism.
Keywords
