Advances in Simple and Chiral-HPLC Methods for Antiallergic Drugs and Chiral Recognition Mechanism
Imran Ali,
Syed Dilshad Alam,
Rupak Raja,
Shafat Ahmad Khan,
Rushda Anjum,
Arvind Kumar Jain,
Hassan Y. Aboul-Enein,
Marcello Locatelli
Affiliations
Imran Ali
Department of Chemistry, Jamia Millia Islamia, New Delhi 110025, India
Syed Dilshad Alam
Jubilant Biosys Limited, Knowledge Park-II, Greater Noida 201310, India
Rupak Raja
Division of Chemistry, School of Basic and Applied Sciences, Galgotias University, Greater Noida 201310, India
Shafat Ahmad Khan
Division of Chemistry, School of Basic and Applied Sciences, Galgotias University, Greater Noida 201310, India
Rushda Anjum
Division of Chemistry, School of Basic and Applied Sciences, Galgotias University, Greater Noida 201310, India
Arvind Kumar Jain
Division of Chemistry, School of Basic and Applied Sciences, Galgotias University, Greater Noida 201310, India
Hassan Y. Aboul-Enein
Pharmaceutical and Medicinal Chemistry Department, National Research Centre, Dokki, Cairo 12311, Egypt
Marcello Locatelli
Department of Pharmacy, Analytical and Bioanalytical Chemistry, University “G. d’Annunzio” of Chieti-Pescara, Build B, Level 2, Via dei Vestini, 31, 66100 Chieti, Italy
Among many diseases, allergy appears to be a serious problem for human beings. Various forms of allergic disorders make people tense, leading to some other health issues. Many medications, including nonracemic and racemic ones, are used to treat this problem. It is important to have exact analysis strategies just to see any medication side effects, plasma profiles, and working efficiency. Therefore, efforts are made to review simple and chiral HPLC methods for antiallergic drugs; HPLC is the best analytical technique. The highlights in this article include the world scenario, causes of allergy, the effect of allergy on the economy, the mechanism of allergy in humans, classes of antiallergic drugs, simple drugs, chiral drugs, analysis by HPLC, and the chiral recognition mechanism. Moreover, attempts are also made to highlight the management of allergies and future perspectives.
