Piperine: A Mini Review on its Pharmacological Profile and Synthetic Derivatives

Abstract

Piperine, known for its vast biological profile, is obtained from black pepper (Piper nigrum, Family: Piperaceae) which is one of the most commonly used spice in major parts of the world and is known for its pungent taste. Piperine is also found to act as an important bioenhancer by increasing the bioavailability of drug molecules and reducing their dosing frequency and dosage. This review article aims at providing various biological activities exhibited by piperine and its numerous synthetic derivatives in order to get some potential lead molecule for future drug discovery.

Keywords

• piperine
• piper nigrum
• piper longa
• anticancer
• antibacterial
• bioenhancer