Nature Communications (Jan 2021)
Genomic epidemiology of SARS-CoV-2 reveals multiple lineages and early spread of SARS-CoV-2 infections in Lombardy, Italy
- Claudia Alteri,
- Valeria Cento,
- Antonio Piralla,
- Valentino Costabile,
- Monica Tallarita,
- Luna Colagrossi,
- Silvia Renica,
- Federica Giardina,
- Federica Novazzi,
- Stefano Gaiarsa,
- Elisa Matarazzo,
- Maria Antonello,
- Chiara Vismara,
- Roberto Fumagalli,
- Oscar Massimiliano Epis,
- Massimo Puoti,
- Carlo Federico Perno,
- Fausto Baldanti
Affiliations
- Claudia Alteri
- Department of Oncology and Hemato-oncology, University of Milan
- Valeria Cento
- Department of Oncology and Hemato-oncology, University of Milan
- Antonio Piralla
- Molecular Virology Unit, Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo
- Valentino Costabile
- Department of Pathophysiology and Transplantation, University of Milan
- Monica Tallarita
- Molecular Virology Unit, Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo
- Luna Colagrossi
- Microbiology and Diagnostic Immunology Unit, Bambino Gesù Children’s Hospital, IRCCS
- Silvia Renica
- Department of Oncology and Hemato-oncology, University of Milan
- Federica Giardina
- Molecular Virology Unit, Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo
- Federica Novazzi
- Molecular Virology Unit, Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo
- Stefano Gaiarsa
- Molecular Virology Unit, Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo
- Elisa Matarazzo
- Residency in Microbiology and Virology, University of Milan
- Maria Antonello
- Department of Oncology and Hemato-oncology, University of Milan
- Chiara Vismara
- Chemico-clinical and Microbiological Analyses, ASST Grande Ospedale Metropolitano Niguarda
- Roberto Fumagalli
- Department of Anesthesiology, Critical Care and Pain Medicine, ASST Grande Ospedale Metropolitano Niguarda
- Oscar Massimiliano Epis
- Rheumatology Unit, ASST Grande Ospedale Metropolitano Niguarda
- Massimo Puoti
- Infectious Diseases Unit, ASST Grande Ospedale Metropolitano Niguarda
- Carlo Federico Perno
- Microbiology and Diagnostic Immunology Unit, Bambino Gesù Children’s Hospital, IRCCS
- Fausto Baldanti
- Molecular Virology Unit, Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo
- DOI
- https://doi.org/10.1038/s41467-020-20688-x
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 13
Abstract
The Lombardy region of Italy was heavily affected early in the SARS-CoV-2 pandemic. Here, the authors use whole genome sequencing and show that there were multiple introductions into the region, with transmission occurring before the first case was detected.
