The Value of E/e'/Stroke Volume Index in Patients Admitted with Acute Decompensation of Systolic Heart Failure

Abstract

Background: Heart failure (HF) is a global pandemic and a serious health issue in elderly population. It is among the leading causes of mortality, which imposes immense economic burden and premature deaths. In the present study we evaluate the value of E velocity of mitral inflow/E’ wave of mitral annular velocity/stroke volume (E/e'/SV) index in relation to in-hospital outcomes in patients with acute decompensation of systolic HF. Methods: In this descriptive-cross sectional study, 59 patient admitted with the diagnosis of decompensated HF were selected, and echocardiography was done before initiation of treatment. E/e′/SV ratio calculated for them before initiation of treatment, and then this index compared with duration of admission, treatment type, in-hospital mortality, and other echocardiographic finding including tricuspid regurgitation gradient (TRG), right ventricle (RV) size, RV function, and left atrium (LA) size. Pro-brain natriuretic peptide (Pro-BNP) and cardiac troponin-I (cTN-I) levels were also recorded. Findings: There was a significant statistical relationship between E/e’/SV index with LV and RV function, ejection fraction (EF), and functional class (FC) factor, as well as prior hospital admissions rate. Conclusion: According to the results of present study, E/e’/SV index is not related to the severity of disease, but has a significant relationship with FC and the number of previous admissions.

Keywords

• heart failure
• stroke volume
• prognosis
• hospitalization