STUDY REGARDING THE USE OF IL-1β IN DIFFERENT TYPES OF FIXED DENTAL RESTAURATIONS

Abstract

Aim The aim of this study is to quantify secretory interleukin 1beta (IL-1β) in crevicular fluid, and to establish a possible link between the values of this parameter and three types of fixed dental restaurations: porcelain fused to metal crown; all ceramic; zirconium ceramic. Material and Method The study was made using three groups of 10 subjects for each fixed dental restauration,The crevicular fluid was collected according to the recommendations of the World Health Organization and quantitative determinations of IL-1 β were made by ELISA method. Results The results show that the values of the IL-1 β in the crevicular fluid have the highest level for the subjects with porcelain fused metal crown ( 89+11.08 pg/mL) and the lowest value was determined at zirconium ceramic restauration (39.3+5.84 pg/mL). Also, there are differences with statistical significance between the IL-1 β before and after three month after the oral rehabilitation using porcelain fused to metal restauration ( p<0,0001); there are no difference with statistical significance between the value of IL-1 β before and after the oral rehabilitation using zirconium ceramic restauration (p=0,41) and all ceramic restauration.( p=0,59). In the same time, results show that there is a positive correlation between the value of the probing depth and IL-1 β only at the porcelain fused to metal before (r=0.698) and after (r=660) fixed dental restauration. Conclusions IL-1 β can be used as markers to assess the evolution of oral rehabilitation after fixed dental restaurations.

Keywords

• fixed dental restauration
• interleukin-1beta
• oral rehabilitation