Nature Communications (Jan 2022)

A bioactivated in vivo assembly nanotechnology fabricated NIR probe for small pancreatic tumor intraoperative imaging

  • Han Ren,
  • Xiang-Zhong Zeng,
  • Xiao-Xiao Zhao,
  • Da-yong Hou,
  • Haodong Yao,
  • Muhammad Yaseen,
  • Lina Zhao,
  • Wan-hai Xu,
  • Hao Wang,
  • Li-Li Li

DOI
https://doi.org/10.1038/s41467-021-27932-y
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 13

Abstract

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Fluorescence probes for detecting tumours during surgery can suffer from poor accumulation and short imaging windows. Here, the author develop fluorescence probes with multiple motifs that permit enhanced circulation times, tumour targeting and use the probes to image pancreatic cancer in mice