PLoS ONE (Jan 2022)

Cardiovascular correlates of sleep apnea phenotypes: Results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

  • Benson Wu,
  • Wassim Tarraf,
  • Douglas M Wallace,
  • Ariana M Stickel,
  • Neil Schneiderman,
  • Susan Redline,
  • Sanjay R Patel,
  • Linda C Gallo,
  • Yasmin Mossavar-Rahmani,
  • Martha L Daviglus,
  • Phyllis C Zee,
  • Gregory A Talavera,
  • Daniela Sotres-Alvarez,
  • Hector M González,
  • Alberto Ramos

DOI
https://doi.org/10.1371/journal.pone.0265151
Journal volume & issue
Vol. 17, no. 4
p. e0265151

Abstract

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BackgroundIdentifying Obstructive Sleep Apnea (OSA) phenotypes among middle-aged and older Hispanics/Latinos can facilitate personalized care, better inform treatment decisions, and could lead to improved clinical outcomes.MethodsWe focused on middle-aged and older adults (ages ≥45-74 years at baseline) with an apnea-hypopnea index (AHI) ≥5 from the HCHS/SOL (2008-2011) (unweighted n = 3,545). We used latent class analyses (LCA) to identify empirical and clinically meaningful OSA phenotypes. Sleep variables included AHI, percent sleep time SpO2ResultsAverage AHI, ESS, WHIIRS, and sleep duration were 18.1±19.5, 6.3±6.1, 7.4±6.6, and 7.8±1.7 hours, respectively, and 2.9% had zero percent time SpO2 ConclusionsOSA subtypes in diverse U.S. Hispanic/Latino adults have different cardiovascular complications. More targeted research, that takes these variations into account, could help ameliorate Hispanic/Latino sleep and cardiovascular health disparities.