A case of bone lesion in a patient with relapsed chronic lymphocytic leukemia and review of the literature

Abstract

Abstract Skeletal involvement in CLL is very rare. We present a case of ileum bone lesion during in a patient receiving 5th line of therapy. Despite radiotherapy and salvage therapies, subsequent bone lesions led to a fatal outcome. Further studies on the mechanism by which bone disease develops are currently needed.

Keywords

• chronic lymphocytic leukemia
• hypercalcemia
• osteolysis