A synthetic biochemistry platform for cell free production of monoterpenes from glucose

Tyler P. Korman; Paul H. Opgenorth; James U. Bowie

doi:10.1038/ncomms15526

Nature Communications (May 2017)

A synthetic biochemistry platform for cell free production of monoterpenes from glucose

Tyler P. Korman,
Paul H. Opgenorth,
James U. Bowie

Affiliations

Tyler P. Korman: Department of Chemistry and Biochemistry, UCLA-DOE Institute, Molecular Biology Institute, University of California
Paul H. Opgenorth: Department of Chemistry and Biochemistry, UCLA-DOE Institute, Molecular Biology Institute, University of California
James U. Bowie: Department of Chemistry and Biochemistry, UCLA-DOE Institute, Molecular Biology Institute, University of California

DOI: https://doi.org/10.1038/ncomms15526
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 8

Abstract

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Terpenes are bioactive natural products derived from plants with several commercial applications. Here, the authors engineer a cell-free system composed of 27 enzymes that convert glucose into terpenes, highlighting the potential of synthetic biochemistry approaches for biocompounds production.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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