Hippocampal cells segregate positive and negative engrams

Monika Shpokayte; Olivia McKissick; Xiaonan Guan; Bingbing Yuan; Bahar Rahsepar; Fernando R. Fernandez; Evan Ruesch; Stephanie L. Grella; John A. White; X. Shawn Liu; Steve Ramirez

doi:10.1038/s42003-022-03906-8

Communications Biology (Sep 2022)

Hippocampal cells segregate positive and negative engrams

Monika Shpokayte,
Olivia McKissick,
Xiaonan Guan,
Bingbing Yuan,
Bahar Rahsepar,
Fernando R. Fernandez,
Evan Ruesch,
Stephanie L. Grella,
John A. White,
X. Shawn Liu,
Steve Ramirez

Affiliations

Monika Shpokayte: Graduate Program for Neuroscience, Boston University
Olivia McKissick: Neuroscience Graduate Program, Brown University
Xiaonan Guan: Department of Physiology and Cellular Biophysics, Columbia University Medical Center
Bingbing Yuan: Whitehead Institute for Biomedical Research, MIT
Bahar Rahsepar: Department of Biomedical Engineering, Boston University
Fernando R. Fernandez: Department of Biomedical Engineering, Boston University
Evan Ruesch: Department of Psychological and Brain Sciences, The Center for Systems Neuroscience, Boston University
Stephanie L. Grella: Loyola University, Chicago Department of Psychology
John A. White: Department of Biomedical Engineering, Boston University
X. Shawn Liu: Department of Physiology and Cellular Biophysics, Columbia University Medical Center
Steve Ramirez: Department of Psychological and Brain Sciences, The Center for Systems Neuroscience, Boston University

DOI: https://doi.org/10.1038/s42003-022-03906-8
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 15

Abstract

Read online

The hippocampus contains neurons that correspond to two partially non-overlapping sets of positive and negative engrams, which may be distinguished by molecular, cellular, and projection-specific features.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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