Nature Communications (Jan 2019)

Ultrafast data mining of molecular assemblies in multiplexed high-density super-resolution images

  • Yandong Yin,
  • Wei Ting Chelsea Lee,
  • Eli Rothenberg

DOI
https://doi.org/10.1038/s41467-018-08048-2
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 7

Abstract

Read online

Analyzing the organization of molecular complexes in multi-color single-molecule localization microscopy data requires heavy computation resources that are impractical for laboratory computers. Here the authors develop a coordinate-based Triple-Correlation algorithm with improved speed and reduced computational cost.