The relationship between H2FPEF score and thrombus burden in patients with ST elevation myocardial infarction

Abstract

Background and Aim: The presence of intracoronary thrombus (ICT) is known to be associated with poor clinical outcomes, including death, in patients diagnosed with ST-segment elevated myocardial infarction (STEMI). Despite this, the predictors of ICT are still uncertain. The aim of our study was to investigate the relationship between thrombus burden (TB) and obesity (H), hypertension (H), atrial fibrillation (F), pulmonary hypertension (P), an age >60 years (E), and E/e' > 9 (F) (H2FPEF) score in STEMI patients. Methods: One hundred consecutive STEMI patients were included in the study. Patients were divided into two groups according to the low TB (grades 0–3) and high TB (HTB) (grades 4 and 5) in comparison with the TB grade before percutaneous coronary intervention in coronary angiographic imaging. H2FPEF score was calculated for all patients. Results: The H2FPEF score was higher in the HTB group (2.94 ± 1.68 vs. 1.62 ± 1.15, P < 0.001). In STEMI patients, the red cell distribution width (odds ratio [OR]: 2.443, 95% confidence interval [CI]: 1.382–4.316; P = 0.002) and H2FPEF score (OR: 2.360, 95% CI: 1.447–3.847; P = 0.001) were independent predictors of HTB. H2FPEF score above a cutoff level of two predicted HTB with a sensitivity of 78% and a specificity of 50%. Conclusion: H2FPEF score may be used as a useful score in predicting HTB in STEMI patients.

Keywords

• h2fpef score
• st-segment elevated myocardial infarction
• thrombus burden