Hidradenitis suppurativa: an update on connecting the tracts [version 1; referees: 3 approved]

Abstract

Hidradenitis suppurativa (HS) is a devastating disease involving abscesses, sinus tracts, and inflammation classically affecting the axilla, groin, and/or anogenital region. Although the disease pathogenesis is not fully understood, recent advances suggest that HS pathology runs much deeper than the cutaneous manifestations. It is now believed that HS is a systemic inflammatory disease that gives rise to the characteristic cutaneous manifestations. This disease is problematic for both patients and physicians to manage because of a variety of diagnostic and management difficulties. This article seeks to provide updates on the current understanding of HS to increase awareness and improve management.

Keywords

• Acne-Like Disorders
• Antimicrobials & Drug Resistance
• Cellular Microbiology & Pathogenesis
• Coronary Artery Disease
• Dermatologic Pathology
• Environmental Microbiology
• Immunopharmacology & Hematologic Pharmacology
• Inflammatory Bowel Disease
• Innate Immunity
• Leukocyte Signaling & Gene Expression
• Medical Genetics
• Medical Microbiology
• Musculoskeletal Pharmacology