Paediatric orodispersible lozenges produced by moulding process: quality and stability control

Abstract

Active pharmaceutical ingredients for paediatric patients are formulated at hospital pharmacy services and compounding pharmacies when they are not commercially available. This work evaluated the quality and stability of lozenges, an orodispersible dosage form, elaborated by a simple and low-cost moulding process.

Keywords

• hydrochlorothiazide
• drug compounding
• hplc
• mass uniformity
• dosage units uniformity
• disintegration