Research progress on ocular biomarkers for the occurrence and progression of retinal vein occlusion

Abstract

The second most prevalent retinal vascular disease after diabetic retinopathy(DR)is retinal vein occlusion(RVO). Ocular biomarkers, including disorganization of retinal inner layers(DRIL), paracentral acute middle maculopathy(PAMM), prominent middle limiting membrane(p-MLM), hyperreflective foci(HRF), subretinal fluid(SRF), ellipsoid zone(EZ), external limiting membrane(ELM), superficial capillary plexus(SCP), and deep capillary plexus(DCP), etc., are indicators or signs derived from auxiliary examinations that can anticipate the onset and progression of diseases as well as the final visual outcome, according to research published in recent years. In our study, we evaluated the ocular biomarkers of RVO in the hopes that these markers would offer a multifaceted picture of the onset and development of RVO, assist in determining the prognosis of RVO, provide a more thorough understanding of the disease and avoid the severe vision impairment of RVO.

Keywords

• retinal vein occlusion
• ocular biomarkers
• optical coherence tomography
• ischemia
• visual acuity