PERFORMANCE OF PROMIS-29 (PATIENT REPORTED OUTCOMES MEASUREMENT INFORMATION SYSTEM-29) IN PATIENTS OF RHEUMATIOD ARTHRITIS

Abstract

Objective: To determine the performance of patient reported outcome measurement information system in patients with rheumatoid arthritis in our setup. Study Design: Cross sectional study. Place and Duration of Study: Division of Rheumatology, Fatima memorial hospital, Lahore Pakistan, from May 2019 to Jul 2019. Methodology: A total of 191 patients of either gender, aged more than 16 years with sero +ve rheumatoid arthritis were included in the study. Results: Majority of patients 156 (81.67%) were female and male 35 (18.32%) with mean age 38 ± 12.19 years. Diagnosed as rheumatoid arthritis and compliant with csDMARDs. Out of all these, majority were in low disease activity (LDA) 72 (38%), remission 62 (32%), moderate 42 (22%) and high disease activity 16 (8%). Mean T-score of all measures showed variations of scores as disease progresses. For all measures, mild change was noted between low disease activity and moderate disease activity whereas high difference was seen in remission and high disease activity. Highest correlations were seen among similar constructs of physical health, mental health, and social health. Fatigue was strongly correlated with social role and social activity. Conclusion: There was a considerable impact of rheumatoid arthritis on physical, social and mental health calculated with patient reported outcomes measurement information system-29 (PROMIS-29).

Keywords

• disease activity score-28
• disease modifying anti rheumatic drugs
• low disease activity
• patient reported outcome measurement information system-29
• rheumatoid arthritis